NetworkNewsBreaks – Lantern Pharma (NASDAQ: LTRN) Advances AI-Driven Oncology Pipeline, Establishes Open Medicine AI

Lantern Pharma (NASDAQ: LTRN), reported second-quarter 2026 operational and financial results, highlighting progress across its AI-driven oncology pipeline and the establishment of Open Medicine AI (“OMAI”) as a separate company. Emerging data from the Phase 2 HARMONIC(TM) trial showed LP-300’s progression-free survival benefit deepening with treatment duration in patients with EGFR exon 21 L858R mutations, while the FDA reviewed key protocol amendments without objection. The European Medicines Agency cleared an investigator-initiated Phase 1b/2 trial of LP-184, or zirdafulven, in biomarker-selected advanced bladder cancer, while the U.S. Patent and Trademark Office issued a Notice of Allowance covering a three-gene patient-selection signature for LP-184. In August, Lantern established OMAI as a wholly owned subsidiary and entered into board-approved commercial licensing agreements for the multi-agentic AI co-scientist platform previously launched as withZeta.ai.

Lantern reported second-quarter loss from operations of approximately $3.5 million, down about 25% from $4.7 million a year earlier, while R&D expenses declined 42% to approximately $1.8 million. Net loss was approximately $7.1 million, or $0.57 per share, compared with $4.3 million, or $0.40 per share, a year earlier, with the increase largely reflecting approximately $3.6 million of warrant-related expense. Cash, cash equivalents and marketable securities totaled approximately $7.4 million as of June 30, 2026.

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ABOUT LANTERN PHARMA INC.

Lantern Pharma Inc. (Nasdaq: LTRN) is a clinical-stage precision oncology company leveraging AI, machine learning, and its proprietary RADR(R) platform to transform the development of cancer therapies. Lantern’s clinical pipeline includes LP-184 (acylfulvene), LP-284 (a TC-NER targeting compound in hematologic and solid tumors), and LP-300 (cisplatin/ethacraplatin analog), which is being evaluated in the HARMONIC Phase 2 trial in never-smoker patients with relapsed advanced lung adenocarcinoma following TKI treatment. LP-184 is also being developed for pediatric CNS cancers through Starlight Therapeutics, Lantern’s wholly owned CNS-focused subsidiary. withZeta.ai , Lantern’s multi-agentic AI co-scientist platform, is now commercially available as a subscription-based research platform for the global biomedical and drug development community, representing a new revenue stream for the Company. Lantern operates an AI Center of Excellence in Bengaluru, India and is headquartered in Dallas, Texas.

NOTE TO INVESTORS: The latest news and updates relating to LTRN are available in the company’s newsroom at https://nnw.fm/LTRN

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