Curated News
By: NewsRamp Editorial Staff
August 28, 2025
MyBioSource Launches New Calretinin Antibody for Neuroscience Research
TLDR
- MyBioSource's new sheep anti-rat calretinin antibody provides researchers with a competitive edge in neurobiology studies through cross-species reactivity and high specificity.
- The antibody targets calretinin at 29 kDa, is purified with protein A for low background, and is validated for Western blot, IHC, and immunofluorescence applications.
- This research tool advances understanding of neuroprotection and calcium signaling, potentially contributing to future treatments for neurodegenerative diseases and neurological disorders.
- Discover how a single antibody can cross-react with multiple species and unlock secrets of calcium regulation in neurons and auditory systems.
Impact - Why it Matters
This development matters because calretinin research is crucial for understanding neurodegenerative diseases like Alzheimer's and Parkinson's, as well as auditory disorders and calcium-related cellular mechanisms. The availability of high-quality, validated antibodies accelerates neuroscience research, potentially leading to breakthroughs in understanding brain function and developing treatments for neurological conditions. For researchers, this means access to a reliable tool that can cross-react with multiple species, saving time and resources while ensuring experimental consistency. The advancement supports the broader scientific community's efforts to unravel complex neurological pathways that affect millions worldwide.
Summary
MyBioSource, a leading provider of high-quality life science reagents based in San Diego, has expanded its research catalog with the introduction of a new Sheep anti-Rat Calretinin Polyclonal antibody (MBS502148). This specialized anti-CALB2 antibody is specifically designed for neuroscience researchers studying calretinin (CALB2), a crucial calcium-binding protein that plays vital roles in neuroprotection, cellular calcium signaling, and neuronal homeostasis. The antibody targets the 29kDa calretinin protein and has been validated for multiple research applications including Western Blot, Immunohistochemistry, and Immunofluorescence techniques.
The antibody offers significant advantages for the scientific community, featuring Protein A purification for high specificity and low background noise, along with potential cross-reactivity with mouse, human, and non-human primate samples due to 100% sequence homology. MyBioSource, founded in 2006 by scientists and now headquartered in Southern California, specializes in providing essential research tools including antibodies, ELISA kits, and PCR kits to support academic and life science research. The company emphasizes that this antibody is intended for research use only and not for diagnostic or clinical applications, requiring researchers to follow appropriate laboratory safety protocols.
This addition to MyBioSource's extensive catalog supports critical research areas including neurodegeneration studies, auditory neuroscience, calcium dynamics analysis, and developmental biology. The antibody's stability at -20°C and its validation in formalin or paraformaldehyde perfused rat brain tissues make it particularly valuable for researchers investigating neuronal resistance to excitotoxicity and cellular mechanisms involving calcium buffering. This development represents another step in MyBioSource's commitment to advancing scientific discovery through high-quality, validated research reagents that enable researchers to explore complex biological pathways and mechanisms.
Source Statement
This curated news summary relied on content disributed by 24-7 Press Release. Read the original source here, MyBioSource Launches New Calretinin Antibody for Neuroscience Research
