Curated News
By: NewsRamp Editorial Staff
February 06, 2026
Lionheart Health & Rejuvant Partner in XPRIZE Healthspan Semi-Finals
TLDR
- Lionheart Health's partnership with Rejuvant provides a competitive edge by integrating proven CaAKG supplementation into a comprehensive healthspan program for measurable longevity benefits.
- The KLOTHO-UP Study systematically combines CaAKG supplements, personalized nutrition, bioelectric exercise, and extensive biomarker testing to evaluate coordinated improvements across multiple health domains.
- This integrated healthspan initiative aims to make tomorrow better by extending functional longevity and improving quality of life through scientifically validated aging interventions.
- Lionheart Health's program uses bioelectric muscle stimulation and 461-biomarker testing alongside CaAKG supplements to potentially reverse biological aging markers in participants.
Impact - Why it Matters
This partnership represents a significant advancement in the longevity and healthspan field by combining rigorously researched nutritional interventions with comprehensive biomarker tracking and bioelectric technologies. For individuals interested in healthy aging, this collaboration demonstrates how evidence-based supplementation can be integrated with personalized approaches to potentially improve multiple health domains simultaneously. The multi-modal framework addresses the complex nature of aging by targeting muscle, metabolic, immune, cardiovascular, and brain health through coordinated interventions, moving beyond single-solution approaches. As the global population ages and healthcare systems face increasing pressure from age-related diseases, such integrated approaches could potentially reduce healthcare costs and improve quality of life by extending functional healthspan. The rigorous longitudinal testing protocol sets a new standard for objective measurement of healthspan interventions, providing valuable data that could inform future longevity research and clinical practices.
Summary
Lionheart Health, a regenerative health and longevity technology company, has announced a strategic partnership with Rejuvant, developer of patented Calcium alpha-ketoglutarate (CaAKG) supplements, as part of their participation in the XPRIZE Healthspan Semi-Finals. This collaboration makes Rejuvant's CaAKG supplementation—backed by peer-reviewed research showing improvements in biological age markers—a mandatory core component of Lionheart's KLOTHO-UP™ Study and broader Klotho Wellness Program. Both companies are leveraging this partnership to advance comprehensive approaches to healthspan extension, with Lionheart having been selected as one of the top 40 semi-finalists from over 600 entries in spring 2025.
The integrated KLOTHO-UP™ Study represents a multi-modal healthspan optimization framework that combines Rejuvant's CaAKG with SNiP Nutrition™ personalized supplements, targeted Klotho-focused supplementation, and Lionheart's BodStim™ bioelectric exercise platform. This technology-driven approach reflects Lionheart's philosophy that meaningful healthspan extension requires both lifestyle optimization and advanced biological technologies working in concert. The program's comprehensive nature includes extensive testing protocols at baseline, 3, 6, and 12-month intervals, featuring 461-biomarker blood panels, AI-enhanced full-body MRI, and assessments across muscle health, gut health, immunity, brain health, metabolic regulation, and multiple other domains.
Leadership from both companies emphasizes the significance of this collaboration, with Lionheart Health noting that Rejuvant's CaAKG platform represents "one of the most rigorously studied nutritional interventions in the biological aging space," while Rejuvant expressed excitement about evaluating their supplementation within "one of the most comprehensive, biomarker-driven healthspan programs ever assembled." The longitudinal design enables objective tracking of functional healthspan changes over time rather than reliance on single-endpoint outcomes. Those interested in learning more about this innovative approach to longevity can book a consultation through the Klotho Wellness Program website to explore how these integrated technologies might benefit their health optimization journey.
Source Statement
This curated news summary relied on content disributed by Newsworthy.ai. Read the original source here, Lionheart Health & Rejuvant Partner in XPRIZE Healthspan Semi-Finals
