HeartBeam ECG Algorithm Shows High Accuracy in Heart Attack Detection

HeartBeam (NASDAQ: BEAT), a medical technology company focused on transforming cardiac care by providing powerful cardiac insights, has announced a significant breakthrough in heart attack detection. A peer-reviewed article published in JACC: Advances demonstrated that a risk prediction algorithm incorporating the credit card-sized HeartBeam ECG device can accurately identify heart attack risk in patients presenting with chest pain. The proof-of-concept study evaluated 184 patients and found that the algorithm achieved an “area under the curve” (“AUC”) of 86.5% using a single HeartBeam ECG reading combined with patient risk factors and symptoms. Remarkably, when a personal, symptom-free baseline ECG was available for comparison, the AUC rose to 92.9%. The company stated that these results support heart attack detection as a future indication for the HeartBeam System and advance its broader clinical program.

HeartBeam is creating the first-ever cable-free device capable of collecting ECG signals in 3D, from three non-coplanar directions, and synthesizing the signals into a 12-lead ECG. This platform technology is designed for portable devices that can be used wherever the patient is to deliver actionable heart intelligence. Physicians will be able to identify cardiac health trends and acute conditions and direct patients to the appropriate care – all outside of a medical facility, thus redefining the future of cardiac health management. HeartBeam’s 3D ECG technology received FDA clearance for arrhythmia assessment in December 2024 and the 12-lead ECG synthesis software in December 2025. The Company holds over 20 issued patents related to technology enablement.

This news matters because it represents a major step toward making heart attack detection more accessible and accurate outside of traditional hospital settings. The ability to use a small, portable device to quickly assess heart attack risk could dramatically reduce time to diagnosis and treatment, potentially saving lives. For patients experiencing chest pain, this technology could mean faster, more accurate triage and fewer unnecessary hospital visits. For healthcare systems, it offers a tool to improve emergency care efficiency and reduce costs. As HeartBeam continues to advance its clinical program, the prospect of a credit card-sized ECG device that can reliably detect heart attacks could revolutionize cardiac care, making it more personal, proactive, and convenient for millions of people at risk of heart disease.