Curated News
By: NewsRamp Editorial Staff
February 12, 2026

Soligenix Sets 2026 Milestones for Rare Disease Pipeline, Eyes CTCL Data

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TLDR

  • Soligenix's 2026 milestones, including HyBryte's Phase 3 trial data, offer investors potential first-mover advantage in rare disease markets with unmet medical needs.
  • Soligenix's pipeline progresses methodically: HyBryte's Phase 3 trial has 66 of 80 patients enrolled, with interim analysis in Q2 and top-line data expected in H2 2026.
  • Soligenix's rare disease treatments, like HyBryte for CTCL and SGX945 for Behçet's Disease, aim to improve patient lives by addressing conditions with limited options.
  • Soligenix's $10.5 million cash funds rare disease research, including a light-based CTCL therapy and a ricin vaccine, blending innovation with public health solutions.

Impact - Why it Matters

This news matters because Soligenix's progress in late-stage clinical trials, particularly for HyBryte in cutaneous T-cell lymphoma and other rare diseases, addresses significant unmet medical needs, offering hope for patients with limited treatment options. For investors, the outlined milestones and strategic evaluations signal potential growth and partnership opportunities in the biotech sector, while the company's cash runway through 2026 provides financial stability. The broader impact extends to public health, with vaccine developments targeting threats like ricin and filoviruses, supported by government funding, highlighting Soligenix's role in advancing medical innovation and preparedness.

Summary

Soligenix (NASDAQ: SNGX), a late-stage biopharmaceutical company, has issued a comprehensive shareholder update from President and CEO Dr. Christopher J. Schaber, outlining ambitious 2026 milestones across its rare disease pipeline. The update highlights the anticipated top-line data from the Phase 3 FLASH2 trial of HyBryte (SGX301) for early-stage cutaneous T-cell lymphoma (CTCL), expected in the second half of 2026, with an interim analysis approaching in the second quarter and 66 of 80 patients already enrolled as of February 10. This news, distributed via BioMedWire, a specialized communications platform within the Dynamic Brand Portfolio of IBN, also reviews positive Phase 2a data for SGX945 (dusquetide) in Behçet’s Disease published in Rheumatology (Oxford), encouraging Phase 2a psoriasis results for SGX302, and ongoing strategic evaluations including partnership and M&A opportunities. The company's cash position of approximately $10.5 million as of September 30, 2025, is projected to provide runway through 2026, supporting these critical developments.

The company's Specialized BioTherapeutics segment is advancing HyBryte, a novel photodynamic therapy using safe visible light for CTCL, with plans to seek worldwide regulatory approvals upon successful Phase 3 completion. Additional programs include expanding synthetic hypericin (SGX302) into psoriasis, developing the first-in-class innate defense regulator dusquetide (SGX942) for inflammatory diseases like oral mucositis, and progressing SGX945 in Behçet’s Disease. Meanwhile, Soligenix's Public Health Solutions segment, supported by government funding from agencies like NIAID, DTRA, and BARDA, focuses on vaccine candidates including RiVax for ricin toxin, filovirus vaccines for Marburg and Ebola, and CiVax for COVID-19, utilizing the proprietary ThermoVax heat stabilization platform. This dual focus underscores Soligenix's commitment to addressing unmet medical needs in both rare diseases and public health threats.

For investors and stakeholders seeking the latest updates, the full press release is available through the provided hyperlink, and ongoing news relating to SNGX can be found in the company’s newsroom. This announcement not only details Soligenix's pipeline progress but also emphasizes its strategic positioning for growth, potentially impacting patient care and market dynamics in the biotech sector. The engagement with platforms like BioMedWire ensures broad dissemination of this information, cutting through market noise to reach a wide audience of investors, journalists, and the public, thereby enhancing brand awareness and transparency for the company.

Source Statement

This curated news summary relied on content disributed by InvestorBrandNetwork (IBN). Read the original source here, Soligenix Sets 2026 Milestones for Rare Disease Pipeline, Eyes CTCL Data

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