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LIXTE Biotech Targets Cancer Resistance to Boost Existing Therapies

LIXTE Biotechnology (NASDAQ: LIXT) develops LB-100 to target PP2A and overcome cancer treatment resistance, enhancing existing immunotherapies & chemotherapies in clinical trials.

This news matters because it addresses a fundamental limitation in current cancer care: treatment resistance. Even effective immunotherapies and chemotherapies often fail over time as tumors adapt. LIXTE's approach of using a compound like LB-100 to target the PP2A pathway and sensitize cancer cells could potentially extend the effectiveness of existing treatments for patients with aggressive or rare cancers, such as ovarian clear cell carcinoma or soft tissue sarcoma, where options are limited. If successful, this strategy could lead to more durable responses, improved survival rates, and better quality of life for countless patients without waiting for entirely new drugs to be developed from scratch. It represents a pragmatic and potentially faster route to meaningful clinical impact by enhancing the tools already in oncology's arsenal.