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Annovis Bio's Alzheimer's Drug Trial Clears Major Safety Hurdle

Annovis Bio receives positive DSMB safety review for Phase 3 Alzheimer's trial of buntanetap, supporting continuation without modification. Read key updates.

This development matters because Alzheimer's disease affects millions globally with limited effective treatments, creating immense personal, familial, and economic burdens. A positive safety review from an independent board significantly de-risks the clinical pathway for buntanetap, increasing its chances of reaching patients. If successful, this oral therapy could offer a disease-modifying treatment that targets multiple toxic proteins—a departure from current approaches—potentially slowing or halting progression rather than just managing symptoms. For patients and families, it represents hope for improved quality of life; for the healthcare system, it could reduce long-term care costs; and for the biotech sector, it validates a novel mechanism that could inspire further research. The trial's continuation brings us closer to potentially transformative answers in neurodegenerative care.