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Lifordi's Breakthrough ADC Targets Autoimmune Diseases Without Toxicity

Lifordi Immunotherapeutics presents breakthrough data on LFD-200 ADC for autoimmune diseases. Phase 1 RA study underway with no toxicity in primate models.

This development represents a potential paradigm shift in autoimmune disease treatment by addressing the fundamental limitation of glucocorticoid therapies – systemic toxicity that prevents long-term use. For the millions of people living with conditions like rheumatoid arthritis, this could mean access to highly effective anti-inflammatory treatments without the devastating side effects like bone density loss, cortisol suppression, and metabolic complications that currently force patients and doctors to limit steroid use. The successful translation of this technology could transform autoimmune disease management from a balancing act of efficacy versus toxicity to targeted, sustainable treatment approaches that maintain quality of life while effectively controlling disease activity.